the effect of indomethacin on biochemical, functional and superficial symptoms of delayed onset muscle soreness (doms) in untrained men

Authors

bakhtyar tartibian

استادیار فیزیولوژی ورزش گروه تربیت بدنی دانشگاه ارومیه بهروز درفشی

کارشناس ارشد فیزیولوژی ورزش بهزاد حاجی زاده ملکی

کارشناس ارشد فیزیولوژی ورزش اصغر توفیقی

استادیار فیزیولوژی ورزشی

abstract

the purpose of this study was to examine the effect of indomethacin on biochemical, functional and external symptoms of delayed onset muscle soreness (doms) following eccentric exercise. for this purpose, 20 untrained, healthy male volunteers (age 25.8+6.9 years and fat 15.9+9.3 %) were selected and randomly divided into experimental (n=10) and placebo (n=10) groups. in a double blind study, subjects were asked to consume 75mg/d indomethacin or placebo for 5 days before and 48 hours after eccentric exercise protocol. doms was induced using controlled plantar flexion causing eccentric contraction of tibialis anterior muscle. the rate of prostaglandins e2 (pge2), perceived pain, foreleg circumference, range of motion in foot joint were measured before, immediately, 24 and 48 hours after eccentric protocol. the results indicated that indomethacin failed to prevent the increased pge2, pain, soreness, inflammation and reduction in range of motion in foot joint immediately after exercise. however, pge2 levels decreased significantly 24 hours (p=0.001) and 48 hours (p=0.001) after exercise. significant changes (p

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Acute effects of ginger extract on biochemical and functional symptoms of delayed onset muscle soreness

  Background: Inflammation and pain induced by delayed onset muscle soreness (DOMS) as a result of eccentric exercise (EE) or unaccustomed activity cause some difficulties in exercise for athletes. The purpose of this study was to survey the effect of ginger extract on biochemical and functional symptom of delayed onset muscle soreness.   Methods : In a quasi-experimental study, 36 healthy fema...

full text

The Effect of Curcumin Supplementation on Selected Markers of Delayed Onset Muscle Soreness (DOMS)

Inflammation and pain induced by delayed onset muscle soreness (DOMS) can be induced by eccentric exercise or an unaccustomed activity. The condition can causes problems in exercising and for athletes. The purpose of this study was to assess the effect of 150mg curcumin supplementation immediately after intensive eccentric exercise. Evaluations were made for total antioxidant Capacity (TAC), mu...

full text

The effect of L-Arginine supplementation on Delayed Onset Muscle Soreness (DOMS) after eccentric heavy exercise

Introduction: L-Arginine supplementation improves antioxidant defenses through L-Arginine/nitric oxide pathways. This investigation assesses the influences of acuteL-Arginine supplementation on selected markers of delayed onset muscle soreness (DOMS) after one by one heavy eccentric exercise in healthy young females. Methods: Twelve healthy young females students of the University of Mohaghegh...

full text

acute effects of ginger extract on biochemical and functional symptoms of delayed onset muscle soreness

background: inflammation and pain induced by delayed onset muscle soreness (doms) as a result of eccentric exercise (ee) or unaccustomed activity cause some difficulties in exercise for athletes. the purpose of this study was to survey the effect of ginger extract on biochemical and functional symptom of delayed onset muscle soreness.   methods : in a quasi-experimental study, 36 healthy female...

full text

Vibration Therapy in Management of Delayed Onset Muscle Soreness (DOMS).

Both athletic and nonathletic population when subjected to any unaccustomed or unfamiliar exercise will experience pain 24-72 hours postexercise. This exercise especially eccentric in nature caused primarily by muscle damage is known as delayed-onset muscle soreness (DOMS). This damage is characterized by muscular pain, decreased muscle force production, reduce range of motion and discomfort ex...

full text

Delayed-Onset Muscle Soreness Symptoms

Objective: We investigated the effects of pulsed ultrasound on swelling, muscle soreness perception, relaxed-elbow extension angle, and muscular strength. Design and Setting: Eight sets of concentric and eccentric actions induced delayed-onset muscle soreness of the elbow flexors. Group 1 received 20% pulsed ultrasound treatments (1 -MHz, 7 minutes, 1.5 W/cm2 temporal peak intensity) twice a da...

full text

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023